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Simmons Faculty Member Awarded National Science Foundation Grant
Assistant Professor John Young to lead project to advance knowledge about limb generation processes in frogs

Boston, Mass. (February 8, 2021) – Simmons University announced today that Assistant Biology Professor John Young has received a grant from the National Science Foundation to study the limb generation process in tadpoles prior to their metamorphosis.
The three-year, $315,757 Standard Grant will enable Young and his team to better understand how animals, such as the tadpoles of frogs, are capable of making a limb when they are no longer embryos. Through traditional methods and newly available genetic tools, the team will work to discover what cells in the tadpole generate limbs and how the genes that regulate their development are controlled.
“In this era of so many scientific advances, we still lack a solid understanding of how amphibians form limbs prior to metamorphosis,” said Young. “Most organisms with arms or legs are hatched or born with largely functional limbs. This important study will enable us to further our knowledge about alternative methods of limb creation that exist in nature, while providing relevant information that can be applied to other organisms, including humans.”
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The research project will be carried out with the help of Simmons undergraduate students and in collaboration with Harvard Medical School.
“We are thrilled to announce this grant, which will not only help advance our understanding of a key biological process, but also give our students the opportunity to participate in an NSF-funded project,” said Lepaine Sharp-McHenry, Dean of the College of Natural, Behavioral, and Health Sciences at Simmons. “John’s enthusiasm for biology and expertise are showcased every day in the classroom, and we’re excited to have him lead this promising research project.”
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The project, which will begin this spring, is among the first to study frog limb generation after the embryo stage.
“I’m proud to lead this initiative that will continue to advance women in science and enable more students to participate in cutting-edge research,” added Young. “Our students are incredibly talented and I’m grateful to have the opportunity to share my excitement for this area of developmental biology with them during this study.”
About Simmons University
Located in the heart of Boston, Simmons is a respected private university offering more than 50 majors and programs for undergraduate women and graduate programs open to all on campus, in blended formats, or entirely online in nursing and health sciences, liberal arts, business, communications, social work, public health, and library and information science. Founded in 1899, Simmons has established a model of higher education that other colleges and universities are only recently beginning to adapt: the combination of education for leadership in high-demand professional fields with the intellectual foundation of the liberal arts. The result is a Simmons graduate prepared not only to work, but to lead in professional, civic, and personal life — a vision of empowerment that Simmons calls preparation for life’s work. Follow Simmons on Twitter at @SimmonsUniv, and on LinkedIn at https://www.linkedin.com/school/simmons-university/.
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