At least one person died Saturday when a vehicle ran off the road and crashed in Campo.
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A man was killed when he crashed a pickup into a concrete barrier near San Ysidro, authorities said.
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A man is in federal custody after a failed attempt to enter the United States by speeding through the San Ysidro Port of Entry.
Paramedics took the 27-year-old motorcyclist to a hospital, where he was pronounced dead.
A 22-year-old motorcyclist was killed in a collision in Otay Mesa, authorities reported.
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The 45-minute pursuit ended with the motorist's arrest at a South Bay church.
A pedestrian was severely injured in a traffic accident on a Chula Vista street, authorities reported.
The motorist who fled the scene of the accident remained unidentified and at large.
A motorist was killed early Wednesday in a solo car crash on Interstate 805 in San Ysidro.
Three people were killed Friday in a fiery head-on collision involving a wrong-way driver on southbound I-5 in San Ysidro.
The man was pronounced dead at the scene, authorities said.
A dozen people died at the scene of the wreck, and another victim was pronounced dead a short time later at a hospital, authorities said.
A speeding SUV collided with three other vehicles in Chula Vista's Otay Ranch neighborhood, police said.
A passenger died following a solo vehicle crash on a National City roadway, police said.
A motorist died after crashing into parked vehicles at a Chula Vista street corner, police said.
The Metropolitan Transit System bus was headed east on East Palomar Street in Chula Vista when the driver lost control of it, police said.
A man was killed and three women were injured in a crash on a state Route 54 off-ramp in the unincorporated Bonita area, police said.
Eddy Lopez of Chula Vista died over the weekend in a suspected DUI-related single-vehicle freeway crash near the U.S.-Mexico border.
The driver was arrested on suspicion of driving under the influence, officials said, and was then released to a hospital for treatment.
Residents who live near the interchange are advised to expect construction noises and the use of machinery during the nighttime work period.
SANDAG and Caltrans will begin five nights of road work on Interstate 805 Sunday from 9 p.m. to 5 a.m.
The Imperial Beach resident crashed on state Route 79 southeast of Palomar Mountain in Warner Springs, authorities reported.
All northbound lanes were closed early Monday morning to allow border agents to add more protective barriers, officials said.
Detours will be in place during the closures both nights, but motorists are urged to avoid the area and use alternate routes, if possible.