A southbound stretch of the road will remain closed after a fire damaged a building on Christmas, requiring the structure to be demolished.
The street closures will start to take affect at 3 p.m. Friday and last through this weekend.
State Street will be closed between 2 to 9 p.m. Thursdays between Second and Fourth streets in downtown Los Altos, police said.
PG&E will be putting in a gas pipeline on the street near the I-280 turnoff, thus prompting expected traffic delays.
The incident was reported around 9:53 a.m.
The incident was reported at 3:32 p.m. Wednesday.