5 Things To Know About Matthew Perry's Death Investigation

LOS ANGELES, CA — Police have arrested at least one person in connection with the death of "Friends" actor Matthew Perry, months after he was found dead in his Pacific Palisades home, according to multiple media reports.

Here are five things to know about the case:

1) A Doctor Was Arrested

At least one of the suspects arrested was a medical doctor, according to TMZ, which broke the story citing unnamed law enforcement sources.

2) Ketamine's Role

The Los Angeles Police Department Federal authorities had been investigating the role of ketamine in Perry's death and how he obtained enough to kill him. The 54-year-old actor was found dead in the hot tub at his Pacific Palisades home on Oct. 28. The cause of death was listed as "the acute effects of ketamine."

"Contributing factors in Mr. Perry's death include drowning, coronary artery disease and the effects of buprenorphine, used to treat opioid use disorder. The manner of death is accident," the medical examiner's office said in a statement.

3) Levels Didn't Make Sense

Ketamine can be used in the treatment of depression. However, the medical examiner said Perry’s last treatment 1 1/2 weeks earlier wouldn’t explain the levels of ketamine found in his blood at the time of his death. The drug is typically metabolized in a matter of hours.

4) There Were Two Doctors Treating Perry

At least two doctors were treating Perry, a psychiatrist and an anesthesiologist who served as his primary care physician, the medical examiner’s report said. No illicit drugs or paraphernalia were found at his house.

5) Perry Had Been Touting His Sobriety

At the time of his death, Perry had been celebrating his sobriety and speaking openly about his longtime struggle with drugs and alcohol. His unflinching memoir about the heights of fame and the depth of addiction included a harrowing account of an emergency surgery following a gastrointestinal perforation, which nearly took his life.

There was no evidence of illicit drugs in Perry's system when he died, according to the medical examiner's report on the actor's death.

City News Service and the Associated Press contributed to this report