The 76-year-old woman died at the scene of the crash, according to the California Highway Patrol.
Neither drugs nor alcohol were believed to be a factor in the collision, the CHP said.
The 54-year-old man was from San Marcos, according to the CHP.
The motorcyclist was ejected onto the roadway and died due to his injuries, according to the CHP.
DUI death of toddler, wife confesses to hitman attempt on husband & more police news this week from San Diego County.
Area couple dies in plane crash, DUI checkpoint arrests, drug-smuggling bust & more police and fire news this week from San Diego County.
The man was found with gunshot wounds inside a vehicle in the intersection of state Route 78 and Haverford Road, authorities said.
DNA leads to murderer's acquittal after 40 years, 14-year-old shot outside house party & more police news this week from San Diego County.
The deadly crash happened on northbound state Route 67 in Ramona, according to the California Highway Patrol.
The Ramona Sheriff's Substation will join law enforcement agencies across the nation to promote strong police-community partnerships.
Stick-up suspect sought, stolen-property viewing planned, sidewalk vendor crackdown & more police news this week from San Diego County.
East County murder-suicide, fatal shooting near Palomar College, body found near airport & more police news this week from San Diego County.
Jail overdose, DUI crackdown, stepdad murder conviction, high-rise fire and other police news this week from San Diego County.
Neurosurgeon sentenced, soccer star jailed for smuggling try, mini-mart worker shot and other police news this week from San Diego County.
A look at some of this week's police, fire and courtroom stories from across San Diego County.
Security officers from the Barona Casino shut down Wildcat Canyon Road as authorities responded to the death.
Sheriff's stations and substations have scheduled family-friendly community events across San Diego County to take a stand against crime.
A brush fire Wednesday has scorched about 180 acres. Officials say they now know what caused the blaze.
Crews of firefighters stopped the spread of a five-acre wildfire believed to be caused by a piece of catalytic converter.
A man was airlifted Monday just before his car burst into flames after crashing through a guardrail.
A 90-year-old man died in a head-on collision that pushed his vehicle backward and into the path of another vehicle, authorities said.