The crash was reported at 11:18 a.m. on the San Diego (405) Freeway traveling through Irvine.
Residents were urged to steer clear of the active investigation area while police are on the scene.
The fire was reported just after 8 a.m. Sunday in the 16900 block of Aston Street in Irvine, authorities said.
The 36-year-old woman was accused of using company credit cards at stores such as Amazon, E-bay, PayPal, Target and more.
A 41-year-old San Clemente man was arrested as a result of the crash, police said.
A bicyclist was found critically injured in the Aliso Creek channel Wednesday evening, the Orange County Fire Authority said.
It was the second fatal freeway crash in the area after a 26-year-old man was killed Monday morning in a three-vehicle crash.
The crash was reported Monday morning in south Orange County, according to the California Highway Patrol.
An Irvine attorney was convicted of killing a semi-truck driver when he crashed into a guardrail while drunk in 2019.
The man was leaving his office in the Irvine airport area on Wednesday, Oct. 15 when he was approached by three hooded men.
Two MS-13 gang members were convicted Tuesday of ambushing a 25-year-old man while he was in Lake Forest.
Irvine police sought the public's help in finding a woman who allegedly stole Pokémon cards from the trunk of a car in Orange County.
Two men were convicted Tuesday in a machete and knife attack that killed a man and wounded his girlfriend seven years ago.
The crash was reported at 10:51 a.m. in south Orange County, according to the California Highway Patrol.
A 57-year-old man was convicted Thursday of repeatedly sexually assaulting a girl he is related to, starting when she was 9 years old.
The 35-year-old woman was convicted of fatally stabbing her mother with a screwdriver on Thursday.
The Irvine Police Department dubbed the suspect "Postal Malone" due to his resemblance with the multi-genre musician.
An Irvine couple was charged with multiple felony counts of medical insurance fraud, identity theft and conspiracy.
The two suspects are believed to be responsible for at least 12 additional thefts from businesses in Chino, Encinitas, Costa Mesa and more.
Orange County firefighters were hard at work early Tuesday morning dousing a mobile home fire in Lake Forest.
The fire was reported shortly before 7 a.m. in the 4800 block of Irvine Boulevard, authorities said.
The 42-year-old Orange County man was a "prominent staff member" of Redeemer Church of Orange County in Newport Beach, police said.
Authorities Friday were seeking additional possible victims of a Santa Ana man accused of using his phone to record up a woman's skirt.
A deputy was also hospitalized after being bitten by an Orange County Sheriff's Department K-9 at the scene.
Officers responded to an early morning bomb threat. Here's what happened.
Prosecutors alleged repeated acts of violence by Lake Forest Councilman Benjamin Yu against his girlfriend, including strangling her.
Irvine police investigating two vehicle break-ins spotted a suspected getaway car in a surveillance video.
A 25-year-old woman has agreed to plead guilty to murder and testify against two others in the grisly slaying, according to authorities.
The crash was reported on Sunday afternoon by the Orange County Sheriff's Department.
The once-popular YouTube personality was caught in a crackdown on illegal street racing in the Irvine area.
A 59-year-old man was charged Thursday with multiple sexual assaults on two teenage girls he is related to in Irvine.
This isn't 'Home Alone,' but an opportunity to ensure someone has your back while you're away.
An Irvine animal trainer and his girlfriend were charged in connection with the deaths of at least a dozen dogs, authorities said.
A south Orange County animal trainer and his girlfriend were arrested Thursday when 10 dogs died while in their care, police said Saturday.
A 75-year-old man was sentenced Monday to 12 years in prison for molesting a girl when she was 4 and 5 years old in Irvine.
A 25-year-old man charged Thursday with videotaping underage girls and touching himself at an apartment complex gym and pool in OC.
The Irvine Councilmember encouraged undocumented people to stay home Thursday in an Instagram post as immigration raids continue in OC.
A 45-year-old man was convicted Tuesday of an alcohol-fueled crash in Irvine that killed a young woman.
A 23-year-old Hawthorne man was arrested this week on charges of human trafficking in Orange County, authorities said.
An Orange County Superior Court judge is weighing the defendant's guilt and insanity plea for the 2017 deaths.